15 Feb 2021 Ep. 47: A Critique of The ROS Theory of Obesity (The Croissant Diet Part 1)
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In this episode we discuss:
3:26 – an introduction to The Croissant Diet and Fire In A Bottle
10:04 – an introduction to ROS and the varying ROS-producing effects of fats and carbs
16:10 – the ROS theory of obesity, Randle cycle confusion, and how fat-burning causes physiological insulin resistance
25:30 – the effect of fatty acid saturation on ROS production when oxidized in mitochondria
29:36 – the real problem with PUFA and why they lead to increases in ROS production rather than decreases
42:28 – why the inefficient mitochondrial respiration that’s fueled by fatty acid oxidation and produces excessive amounts of ROS harms our health
47:39 – the problems with the idea of hormesis
58:39 – why fat-burning doesn’t increase fat loss
1:05:45 – anti-hormesis and the bioenergetic view of obesity
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