24 Jul 2023 Ep. 96: Avoid Low-Carb Diets, Fasting, and Caloric Restriction If You Have Hypothyroidism (Hypothyroidism Part 2)
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In this episode we discuss:
1:28 – the factors that affect thyroid hormone production, conversion, transport, and uptake
3:45 – the impact of stress on thyroid hormone production and conversion
5:02 – how the stress hormones and inflammatory cytokines affect thyroid hormone production and conversion
16:44 – thyroid hormones increase sensitivity to stress hormones
21:44 – elevated free fatty acids, especially PUFA, inhibit thyroid hormone binding
23:26 – how a lack of energy prevents the cells from taking up thyroid hormone
30:00 – how oxidative stress affects thyroid hormone production and the effects of TSH on oxidative stress
38:25 – how a low-carb diet affects thyroid hormone production and conversion, causing a hypothyroid state; high-carb diets vs. low-carb diets for thyroid health
47:46 – insulin resistance is associated with reduced thyroid hormone conversion, but this doesn’t mean you should avoid carbohydrates
51:39 – how caloric restriction affects thyroid status
55:04 – the effects of fasting on thyroid status
56:42 – T3 has positive feedback on its own production and what this means for thyroid hormone replacement
1:00:01 – the effects of PUFA and endotoxin on thyroid hormone activity
1:04:30 – the effects of micronutrients, specifically iron, vitamin A, selenium, and iodine, on thyroid hormone production, conversion, and activity
1:16:30 – increased thyroid activity increases macronutrient and micronutrient needs, but also improves micronutrient retention in the long-term
1:19:15 – the effects of environmental toxins (pesticides, industrial chemicals, heavy metals, etc.) on thyroid hormone production, conversion, and activity
1:25:20 – the effect of sleep on thyroid hormone production and conversion
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